Medicinal Chemistry II
Unit 5 Notes
Anti diabetic agents:
Insulin and its preparations
Sulfonyl ureas : Tolbutamide*, Chlorpropamide, Glipizide, Glimepiride.
Biguanides : Metformin.
Thiazolidinediones : Pioglitazone, Rosiglitazone.
Meglitinides : Repaglinide, Nateglinide.
Glucosidase inhibitors : Acrabose,Voglibose.
Local Anesthetics : SAR of Local anesthetics
Benzoic Acid derivatives : Cocaine, Hexylcaine, Meprylcaine, Cyclomethycaine, Piperocaine.
Amino Benzoic acid derivatives : Benzocaine, Butamben, Procaine, Butacaine, Propoxycaine, Tetracaine, Benoxinate.
Lidocaine/Anilide derivatives : Lignocaine, Mepivacaine, Prilocaine, Etidocaine.
Miscellaneous : Phenacaine, Diperodon, Dibucaine.*