Computer Aided Drug Design
Unit 1 Notes
Introduction to Drug Discovery and Development
Stages of drug discovery and development
Lead discovery and Analog Based Drug Design
Rational approaches to lead discovery based on traditional medicine,
Random screening, Non-random screening, serendipitous drug discovery,
lead discovery based on drug metabolism, lead discovery based on
clinical observation.
Analog Based Drug Design : Bioisosterism, Classification, Bioisosteric
replacement. Any three case studies