Biochemistry
Unit 3 Notes
1. Lipid metabolism
β-Oxidation of saturated fatty acid (Palmitic acid)
Formation and utilization of ketone bodies; ketoacidosis De novo synthesis of fatty acids (Palmitic acid)
Biological significance of cholesterol and conversion of cholesterol into
bile acids, steroid hormone and vitamin D
Disorders of lipid metabolism: Hypercholesterolemia, atherosclerosis,
fatty liver and obesity.
2. Amino acid metabolism
General reactions of amino acid metabolism: Transamination,
deamination & decarboxylation, urea cycle and its disorders
Catabolism of phenylalanine and tyrosine and their metabolic disorders
(Phenyketonuria, Albinism, alkeptonuria, tyrosinemia)
Synthesis and significance of biological substances; 5-HT, melatonin,
dopamine, noradrenaline, adrenaline
Catabolism of heme; hyperbilirubinemia and jaundice