Medicinal Chemistry II
Unit 2 Notes
Anti-anginal :
Vasodilators : Amylnitrite, Nitroglycerin, Pentaerythritol tetranitrate, Isosorbide dinitrite, Dipyridamole.
Calcium channel blockers : Verapamil, Bepridil hydrochloride, Diltiazem
hydrochloride, Nifedipine, Amlodipine, Felodipine, Nicardipine, Nimodipine.
Diuretics:
Carbonic anhydrase inhibitors : Acetazolamide, Methazolamide, Dichlorphenamide.
Thiazides : Chlorthiazide, Hydrochlorothiazide, Hydroflumethiazide,
Cyclothiazide,
Loop diuretics : Furosemide*,Bumetanide, Ethacrynicacid.
Potassiumsparing
Diuretics : Spironolactone, Triamterene, Amiloride.
Osmotic Diuretics : Mannitol
Anti-hypertensive Agents : Timolol, Captopril, Lisinopril, Enalapril, Benazepril hydrochloride, Quinapril hydrochloride, Methyldopate hydrochloride,*Clonidine hydrochloride, Guanethidine monosulphate, Guanabenz acetate, Sodium nitroprusside, Diazoxide, Minoxidil, Reserpine, Hydralazine hydrochloride.